| # | Major League Soccer | G | W | D | L | GF | GA | Pts | +- | ||
| # | Eastern Conference | G | W | D | L | GF | GA | Pts | +- | ||
| - | Toronto FC | 34 | 20 | 9 | 5 | 74 | 37 | 69 | 37 | Champions | |
| - | New York City FC | 34 | 16 | 9 | 9 | 56 | 43 | 57 | 13 | ||
| - | Chicago Fire | 34 | 16 | 7 | 11 | 62 | 48 | 55 | 14 | ||
| - | Atlanta United FC | 34 | 15 | 10 | 9 | 70 | 40 | 55 | 30 | ||
| - | Columbus Crew | 34 | 16 | 6 | 12 | 53 | 49 | 54 | 4 | ||
| - | New York Red Bulls | 34 | 14 | 8 | 12 | 53 | 47 | 50 | 6 | ||
| - | New England Revolution | 34 | 13 | 6 | 15 | 53 | 61 | 45 | -8 | ||
| - | Philadelphia Union | 34 | 11 | 9 | 14 | 50 | 47 | 42 | 3 | ||
| - | Montréal Impact | 34 | 11 | 6 | 17 | 52 | 58 | 39 | -6 | ||
| - | Orlando City SC | 34 | 10 | 9 | 15 | 39 | 58 | 39 | -19 | ||
| - | DC United | 34 | 9 | 5 | 20 | 31 | 60 | 32 | -29 | ||
| # | Western Conference | G | W | D | L | GF | GA | Pts | +- | ||
| - | Portland Timbers | 34 | 15 | 8 | 11 | 60 | 50 | 53 | 10 | ||
| - | Seattle Sounders FC | 34 | 14 | 11 | 9 | 52 | 39 | 53 | 13 | ||
| - | Vancouver Whitecaps | 34 | 15 | 7 | 12 | 50 | 49 | 52 | 1 | ||
| - | Houston Dynamo | 34 | 13 | 11 | 10 | 57 | 45 | 50 | 12 | ||
| - | Sporting Kansas City | 34 | 12 | 13 | 9 | 40 | 29 | 49 | 11 | ||
| - | San Jose Earthquakes | 34 | 13 | 7 | 14 | 39 | 60 | 46 | -21 | ||
| - | FC Dallas | 34 | 11 | 13 | 10 | 48 | 48 | 46 | 0 | ||
| - | Real Salt Lake | 34 | 13 | 6 | 15 | 48 | 56 | 45 | -8 | ||
| - | Minnesota United FC | 34 | 10 | 6 | 18 | 47 | 70 | 36 | -23 | ||
| - | Colorado Rapids | 34 | 9 | 6 | 19 | 31 | 51 | 33 | -20 | ||
| - | Los Angeles Galaxy | 34 | 8 | 8 | 18 | 45 | 67 | 32 | -22 |